Pharmacodynamics Amoxicillin is a β-lactam class of antibiotics, with a broad spectrum of antibacterial action. The antimicrobial spectrum and antimicrobial activity were basically the same as that of ampicillin. The antimicrobial activity against most gram-positive bacteria was slightly weaker than that of penicillin, and it was sensitive to penicillinase, so it was ineffective against penicillin-resistant Staphylococcus aureus. It has a strong effect on gram-negative bacteria such as Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella and Pasteurella, but these bacteria are easy to develop drug resistance. Not sensitive to Pseudomonas aeruginosa. Because its absorption in monogastric animals is better than ampicillin and its blood concentration is higher, it has a better effect on systemic infection. It is suitable for respiratory system, urinary system, skin and soft tissue infection caused by sensitive bacteria.
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