(1) This product has synergistic effect when used in combination with aminoglycoside or broad spectrum penicillin.
(2) Ca2+, Mg2+, Fe3+ and Al3+ plasma can chelate with this product, affecting absorption.
(3) Should not be mixed with acid drugs;When used together with theophylline and caffeine, the binding rate of plasma protein can be reduced, the concentration of theophylline and caffeine in blood can be abnormally increased, and theophylline poisoning may even occur.
(4) This product can inhibit the liver drug enzyme, which can reduce the clearance rate of drugs mainly metabolized in the liver and increase the blood drug concentration.
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